Benzothiazolyl and Benzimidazolyl Substituted 1-Iminoisoindolines: Synthesis, Mechanistic Studies and Crystal Structure Determination

Sović, Irena; Orehovec, Iva; Stilinović, Vladimir; Basarić, Nikola; Karminski-Zamola, Grace

doi:10.1007/s00706-016-1796-5

Pregled bibliografske jedinice broj: 750290

Benzothiazolyl and Benzimidazolyl Substituted 1-Iminoisoindolines: Synthesis, Mechanistic Studies and Crystal Structure Determination

Sović, Irena; Orehovec, Iva; Stilinović, Vladimir; Basarić, Nikola; Karminski-Zamola, Grace

Benzothiazolyl and Benzimidazolyl Substituted 1-Iminoisoindolines: Synthesis, Mechanistic Studies and Crystal Structure Determination // Monatshefte für Chemie, 147 (2016), 10; 1825-1837 doi:10.1007/s00706-016-1796-5 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 750290 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Benzothiazolyl and Benzimidazolyl Substituted 1-Iminoisoindolines: Synthesis, Mechanistic Studies and Crystal Structure Determination

Autori
Sović, Irena ; Orehovec, Iva ; Stilinović, Vladimir ; Basarić, Nikola ; Karminski-Zamola, Grace

Izvornik
Monatshefte für Chemie (0026-9247) 147 (2016), 10; 1825-1837

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Heterocycles ; Reaction mechanisms ; Schiff bases ; X-Ray structure determination

Sažetak
New benzothiazolyl and benzimidazolyl substituted 1-iminoisoidolines are prepared in the reaction of o-phthalaldehyde and substituted 2-aminobenzothiazoles and 2-aminobenzimidazoles. The optimization of these reactions is discussed and the reaction mechanisms are proposed based on the experimental findings. Isoindolines with other heterocyclic substituents are prepared as a confirmation of the proposed mechanisms. Molecular and crystal structures of several prepared compounds are determined by a single crystal X-ray diffraction. These structures are found to be in line with projections based on the chemical and spectroscopic properties, and thus offer an additional confirmation of the proposed reaction mechanisms.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA

Projekti:
HRZZ-IP-2013-11-5596 - Sinteza i citostatska ispitivanja biblioteke novih dušikovih heterocikla (SCIENcENTRY) (Raić-Malić, Silvana, HRZZ - 2013-11) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb

Profili:

Nikola Basarić (autor)