Naslov
Summary of information on human CYP enzymes A. Human P450 Metabolism Data

Autori
Rendić, Slobodan

Izvornik
Drug Metabolism Reviews (0360-2532) 34 (2002), 1,2; 83-488

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
P450; CYP enzymes; drugs; chemicals; human; toxicity; inhibitors; inductors; metabolic reactions

Sažetak
This paper is an update of the data on substrates, reactions, inducers and inhibitors of human CYP enzymes published previously by S. Rendic and F. DiCarlo (1), now covering selection of the literature through 2001 in the reference section. The data are presented in a tabular form (Table 1) to provide a framework for predicting and interpreting the new P450 metabolic data. The data are formatted in an Excel format as most suitable for off-line searching and management of the Web-database. The data are presented as stated by the author(s) and in the case when several references are cited the data are presented according to the latest published information. The searchable database is available either as an Excel file (for information contact the author), or as a Web-searchable database (Human P450 Metabolism Database, www.gentest.com) enabling the readers easy and quick approach to the latest updates on human CYP metabolic reactions.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija

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