Naslov
Head position and cerebrospinal fluid pressure in cats

Autori
Radoš, Milan ; Klarica, Marijan ; Kuzman, Tomislav ; Bolanča, Ivan ; Draganić, Pero ; Orešković, Darko ; Bulat, Marin

Izvornik
Periodicum Biologorum (0031-5362) 103 (2001), 4; 339-342

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cerebrospinal fluid; intracranial pressure; head position; postural pressure

Sažetak
Background and Purpose: The intraventricular cerebrospinal fluid (CSF) pressure is measured in animals fixed in stereotaxic apparatus in sphinx position with reference to interaural line. However, control data of CSF pressure in cats vary between various laboratories from 4 cm H2O to 20 cm H2O. We assumed that such variability might be due to different distances between the head holder and the base fo stereotaxic apparatus on which the animal body is positioned. Material and Methods: To explore this assumption we measured intraventricular CSF pressure in chloralose anesthetized cats with head fixed in head holder. The interaural line was taken as zero pressure. Results: Under chloralose anesthesia, CSF pressure was stable during one hour in animals fixed in sphinx position. Selected distances between the head holder and the base of stereotaxic apparatus were 7 cm, 12 cm and 17 cm, while CSF pressures of 11.9 +/- 2.8 H2O, 7.7+/- 1.6 cm H2O and 4.7 +/- 1.8 cm H2O (n=7), respectively, were recorded. Conclusion: Analysis of these results indicates that there is a negative linear relationship (r=-0.99) between CSF pressure and distance between the head holder and the base fo stereotaxic apparatus. Since in previously published papers this distance is not mentioned, our results suggest that great variability of control CSF pressures was due to different distances between head holder and the base of stereotaxic appparatus during CSF pressure measurements.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA