Naslov
Human leptospirosis in Croatia

Autori
Balen Topić, Mirjana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
European meeting of leptospirosis Eurolepto 2012, Abstracts / Ellis, Bill ; Hartskeerl, Rudy ; Milas, Zoran ; Nally, Jarlath ; Picardeau, Mathieu ; - Zagreb : Fakulty of Veterinary Medicine, University of Zagreb, 2012, 37-37

ISBN
978-953-6062-87-4

Skup
European meeting on leptospirosis Eurolepto 2012

Mjesto i datum
Dubrovnik, Hrvatska, 31.05.2012. - 02.06.2012

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Humana leptospiroza; Hrvatska; epidemiologija; klinička slika
(Human leptospirosis; Croatia; epidemiology; clinical presentation)

Sažetak
Title: Human leptospirosis in Croatia Institution: University Hospital for Infectious Diseases „Dr Fran Mihaljevic“, School of Medicine, University of Zagreb ABSTRACT Due to observed changes in epidemiology and in clinical presentation, human leptospirosis has been worldwide recently recognized as a „reemerging“ infectious diseases. Since the first description of the patient with Weil's disease in Croatia in 1935 till nowdays leptospirosis has been in our country the constant object of research of infectous diseases specialists, epidemiologists, immunologists, veterinarians and foresters. The aim of our retrospective cohort study was to asses epidemiological and clinical characteristic of human leptospirosis in Croatia. According to official data, the mean yearly incidence of human leptospirosis from 1990 to 2011 was 1.63/100 000 inhabitans (range per years: 0.27-3.42/100 000 inhabitans). Among reported cases in observed period 22/1614 (1.36%) died. In addition to the majority of sporadic cases, two minor outbreaks in rural areas were recorded. The clinical burden and more detailed epidemiology of 152 patients with serologically proven leptospirosis hospitalized at University Hospital for Infectious Diseases „Dr Fran Mihaljević“ (UHID) in Zagreb in the period 1997-2011 were also studied. Clinical presentations were as expected, with an overall case fatality rate (CFR) of 0.66%. The most commonly established infective serovars were Australis followed by Saxkoebing and Grippotyphosa. In conclusion, we consider that Croatia is one of the countries with the higest incidence of human leptospirosis in Europe. In comparison with previous periods, the mean yearly number of patients with leptospirosis hospitalized at UHID decreased, but among them a rather higher rate of patients with Weil's disease and a higher CFR was observed. According to profile of causative serovars, inland Croatia presents specific „arahic“ natural leptospirosis focus.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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