Naslov
Desmoplastic malignant melanoma. Case report, immunohistochemical observations and review of literature

Autori
Dmitrović, Branko ; Trošić, Ante

Izvornik
Medicinski vjesnik (0350-6487) 23 (1991), 1-2; 45-49

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
desmoplastic malignant melanoma; immunohistochemistry

Sažetak
A case of malignant melanoma with a desmoplastic recurrence and local lymph node metastasis is reported. The local relapse and the axillary metastasis presented the desmoplastic variant without atypical melanocytes that were easily recognised in primary lesion. Histological slides were examined by light microscopy and immunohistochemistry. Melanin could not be demonstrated in either recurrence or metastasis by histochemical tehnique. Immunoperoxidase staining with anti S-100 protein antibody demonstrated diffuse positivity of spindle cells both in relapse and metastasis, allowing the assesment of the depth of invasion. All the sections were negative for vimentin, desmin and neuron-specific enolase.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA