Naslov
Acute interstitial nephritis due to mesalazine : case report

Autori
Tadić, Mario ; Grgurević, Ivica ; Šćukanec- Špoljar, Mira ; Božić, Borka ; Marušić, Srećko ; Horvatić, Ivica ; Galešić, Krešimir

Izvornik
Nephrology (1320-5358) 10 (2005), 2; 103-105

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Glomerulonephritis; Inflammatory Bowel Disease; interstitial nephritis; mesalazine; monitoring renal function

Sažetak
A case of mesalazine-induced acute interstitial nephritis (AIN) in a 41-year-old patient with ulcerative colitis (UC) is reported here. Clinical symptoms such as fever and arthralgia, and laboratory findings such as eosinophilia and renal failure suggested AIN, which was confirmed by biopsy. With withdrawal of mesalazine and intravenous methylprednisolone the patient's renal function was recovered. It is observed that early discontinuation of mesalazine is associated with amelioration of interstitial nephritis in most patients, so the recommendation is that patients receiving mesalazine should undergo routine monitoring of renal function. Delayed diagnosis may lead to permanent renal function impairment.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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