Naslov
UNILATERAL ROSACEA APPEARING AT THE SITE OF CHRONIC RADIODERMATITIS

Autori
Čarija, Antoanela ; Vukšić, Ivan ; Puizina-Ivić, Neira ; Marasović, Dujomir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Skup
18th EADV Congress

Mjesto i datum
Berlin, Njemačka, 07.10.2009. - 11.10.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
rosacea; chronic radiodermatitis; unilateral

Sažetak
Rosacea is a condition that predominantly affects the convexities of the central aspect of the face. In our patient rosacea was predominantly on the left side at the site of chronic radiodermatitis. Rosacea is rarely unilateral. In one epidemiological study 14% of patients had unilateral lesions.1 Sezer and al described a 40-year-old man developing an erythematous rash on the right side of his face 3 weeks after a herpes zoster infection at the same location, a Wolf's isotopic response 2. In our case we could say it is also a case of a Wolf’s isotopic response. Research supports that an immune response of helper-inducer T-cell infiltrates occurs, surrounding the Demodex antigens in patients with rosacea. But is Demodex truly pathogenic? Conflicting evidence indicates that Demodex does not induce an inflammatory response in patients with rosacea. Moreover, Demodex is found in large numbers of healthy individuals without rosacea.5 Two histological studies indicated that inflammatory infiltrates a predominantly perivascular not perifollicular. 6, 7 Our patient has less pilosebaceous units because of the chronic radiodermatitis. That would suggest less Demodex mites, and still rosacea was more present at the site with less Demodex. It seems that in our patient, Demodex is not an important pathogenic factor.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA