Naslov
Acute appendicitis as a complication of varicella : case report

Autori
Pogorelić, Zenon ; Biočić, Mihovil ; Jurić, Ivo ; Milunović, Klaudio Pjer ; Mrklić, Ivana

Izvornik
Acta Medica (Hradec Kralove) (1211-4286) 55 (2012), 3; 150-152

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, case report, stručni

Ključne riječi
Acute appendicitis ; Varicella-zoster virus ; Chickenpox ; Varicella ; Children

Sažetak
Obstruction of the appendiceal lumen is the primary cause of appendicitis. The most common causes of luminal obstruction are fecaliths and lymphoid follicle hyperplasia. Additionally, bacterial infections or enteric and systemic viral diseases can cause a reaction of the lymphoid follicle. An 11-year-old boy with active phase of chickenpox presented on our Pediatric surgery emergency department under the impression of acute appendicitis. An appendectomy was performed on the same day. An inflamed and edematous retrocecal appendix was removed during surgery. Histological investigation of the appendix revealed transmural acute inflammation, with diffuse proliferation of inflammatory cells, with characteristic intranuclear inclusion surrounded by a clear halo. The PCR analysis of peripheral blood and appendix tissue specimen revealed positive VZV DNA. We have shown that varicella-zoster virus infection of the appendix is associated with acute appendicitis and possibly also with severity of the disease.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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