Naslov
Minerals, vitamins and food supplements as fetal malformation risk factors

Autori
Leppee, Marcel ; Culig, Josip ; Boskovic, Jelena ; Eric, Mirela

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
2nd European Public Health Conference, EUPHA, Abstract: The European JOurnal of Public Health 2009 ; 19(Suppl 1):137 / - , 2012

Skup
2nd European Public Health Conference, EUPHA

Mjesto i datum
Łódź, Poljska, 25.11.2012. - 28.11.2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
drug utilization; maternal diet; fetal development

Sažetak
The aim was to determine drug utilization in pregnancy and early postpartum period in Zagreb, and to identify major deviations from the existing trends. The study was performed at university departments and departments of gynecology and obstetrics in four medical institutions in Zagreb. Maternal diet rich in vitamins and minerals is a precondition for normal fetal development ; however, most authors believe that no additional supplementation is needed in case of appropriate diet and adequate intake of all necessary nutrients. The vitamin-mineral complex was most frequently used by pregnant women from Zagreb (n=508 ; 56.9%). Analysis of calcium intake in pregnancy yielded a statistically significant difference at P<0.05 in the rate of congenital malformations between the children born to women with and without calcium intake, suggesting an association of calcium intake and congenital malformations ; however, there was no statistically significant difference at P<0.01. These results substantiated doubts about uncontrolled use of various vitamin-mineral compounds in pregnancy. Ferro-compounds ranked fourth among 20 most commonly prescribed drugs. Iron as isolated preparation was used by 203 (22.7%) and in combination with other minerals and vitamins by almost 2/3 of pregnant women. Analysis of iron use in pregnancy produced a statistically significant difference in the rate of congenital malformations between the children born to mothers with and without iron intake, pointing to an association of iron intake and congenital malformations. This is in contrast to current concepts, since no such association was recorded in previous studies. Our study results support the reports that criticize injudicious iron prescribing, since about 10% of non-pregnant women of reproductive age suffer from anemia anyhow.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA