Pregled bibliografske jedinice broj: 729859
The novel fenoprofenamides - synthesis and spectroscopic characterization
The novel fenoprofenamides - synthesis and spectroscopic characterization // Acta pharmaceutica, 51 (2001), 2; 107-115 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 729859 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The novel fenoprofenamides - synthesis and spectroscopic characterization
Autori
Zovko, Marijana ; Zorc, Branka ; Jadrijević-Mladar Takač, Milena ; Zorc, Davor
Izvornik
Acta pharmaceutica (1330-0075) 51
(2001), 2;
107-115
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Fenoprofen; Fenoprofenamide; Synthesis; Benzotriazole; Prodrug
Sažetak
Synthesis of a series of new fenoprofenamides (3a-j) is described. Amide bonding was achieved by aminolysis of fenoprofen benzotriazolide (2) with various amines: primary, secondary, hydoxylamine and amino acids. The structures of synthesized compounds were fully characterized by IR, 1H and 13C NMR spectroscopies and elemental analysis. The synthesized compounds are potential prodrugs of a well known NSAID fenoprofen.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
Profili:
Milena Jadrijević-Mladar Takač
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus