Naslov
New European guidelines for pulmonary embolism: the role of novel oral direct anticoagulants

Autori
Zaputović, Luka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Cardiologia Croatica. 2014 ; 9(9-10):325-520. / Ivanuša, Mario ; Čikeš, Maja ; Miličić, Davor - Zagreb : Hrvatsko kardiološko društvo, 2014, 333-333

Skup
10. kongres Hrvatskoga kardiološkog društva

Mjesto i datum
Zagreb, Hrvatska, 06.11.2014. - 09.11.2014

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
venous thromboembolism; pulmonary embolism; anticoagulants

Sažetak
The term venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and pulmonary embolism (PE). VTE represents the third most frequent cardiovascular disease with the annual incidence of 100-200 per 100.000 inhabitants. The consequences which may be fatal or lead to chronic disease are often preventable. The European Society of Cardiology has recently published the third release of guidelines for PE, endorsed by the European Respiratory Society. Many facts and recommendations have been retained from previous version, but very important new data and evidence have been summarized, especially on the treatment and prophylaxis of VTE with the new oral direct anticoagulants (NOACs). The principal results of phase III clinical trials with NOACs on the acute phase treatment and standard duration of anticoagulation after PE or VTE have been overviewed, as well for the extended treatment. These results strongly indicate that NOACs are non-inferior in terms of efficacy and possibly safer, particularly in terms of major bleeding, than standard treatment with heparin and vitamin K antagonists. Based on the evidence and permanently growing data, NOACs should be seriously considered as an alternative to standard tretment of VTE and used according to the recommendations published in the practical guide by the European Heart Rhythm Association.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA