Naslov
The role of kidney biopsy in diagnosis of renal parenchymal anomalies in children

Autori
Milosevic, Danko ; Batinic, Danica ; Scukanec-Spoljar, Mira ; Nizic, Ljiljana ; Vrljicak, Kristina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Meeting abstract / Danica Batinić, Danko Milošević - New York (NY) : Springer, 2011, 1694-1695

Skup
Pediatrics, Urology & Nephrology

Mjesto i datum
Dubrovnik, Hrvatska, 14.09.2011. - 17.09.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
kidney biopsy; renal anomalies; children

Sažetak
Objectives and study: Congenital renal parencyhimal anomalies belong in a group of rare kidney diseases associated with the end stage renal failure. Usually presented on ultrasound as “small kidneys”, the diseases assume considerable diagnostic and care workup. We analysed the percentage of renal parenchymal anomalies among kidney biopsies in our population and importance of childen/parents life style recommendations.Methods: A retrospective clinical analysis of kidney biopsies.Results: During past 13 years we peformed 450 kidney biopsies at University Hospital Centre Zagreb and Rijeka in children aged 0–17 years (22.3% of both hospital kidney biopsies, adult patients included). Congenital kidney parenchymal anomalies were diagnosed in 15 children (3.3%). Nephronophtisis was found in 8 children (median age 8.8 years, infants 1/8), oligomeganephronia revealed in 7 (median age 5.6 years, infants 5/7), of whom one child has combined histological picture of oligomeganephonia/interstitial nephritis. All children suffered eventually from progressive renal faulure. In one family we suspect of hereditary type disease. Multiple anomalies can be found in children with both diseases, primarily in oligomeganephronia.Conclusions: Early correct diagnosis enabled us to postpone end stage renal failure by children/parents life style consulting and parental genetic counselling for the future progeny.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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