Pregled bibliografske jedinice broj: 727339
Volatile anesthetic-induced cardiac preconditioning
Volatile anesthetic-induced cardiac preconditioning // Journal of Anesthesia, 21 (2007), 212-219 doi:10.1007/s00540-006-0486-6 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 727339 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Volatile anesthetic-induced cardiac preconditioning
Autori
Stadnicka, Anna ; Marinović, Jasna ; Ljubković, Marko ; Bienengraeber, Martin W. ; Bošnjak, Željko J.
Izvornik
Journal of Anesthesia (0913-8668) 21
(2007);
212-219
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
KATP channel ; Mitochondria ; Myocardium ; Preconditioning ; Volatile anesthetics
Sažetak
Pharmacological preconditioning with volatile anesthetics, or anesthetic-induced preconditioning (APC), is a phenomenon whereby a brief exposure to volatile anesthetic agents protects the heart from the potentially fatal consequences of a subsequent prolonged period of myocardial ischemia and reperfusion. Although not completely elucidated, the cellular and molecular mechanisms of APC appear to mimic those of ischemic preconditioning, the most powerful endogenous cardioprotective mechanism. This article reviews recently accumulated evidence underscoring the importance of mitochondria, reactive oxygen species, and KATP channels in cardioprotective signaling by volatile anesthetics. Moreover, the article addresses current concepts and controversies regarding the specific roles of the mitochondrial and the sarcolemmal KATP channels in APC.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Split
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
