Naslov
Human exposure to ochratoxin A in two cities of Croatia

Autori
Peraica, Maja ; Domijan, Ana-Marija ; Fuchs, Radovan ; Lucić, Ana ; Radić, Božica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Toxicology Letters / - Amsterdam : Elsevier, 2001, 42-43

Skup
EUROTOX 2001.

Mjesto i datum
Istanbul, Turska, 13.09.2001. - 16.09.2001

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Ochratoxin A; Mycotoxin; Blood donors; Healthy population; Croatia; Daily Intake

Sažetak
Humans are exposed to nephrotoxic mycotoxin ochratoxin A (OTA) mostly by ingestion of contaminated food (cereals, pork meat, wine, beer, coffee, and dry fruits). The aim of our investigation was to find out whether the high consumption of fresh and smoked pork meat and wine during winter period influence the exposure to OTA. Blood samples of healthy volunteers were collected by fifty in Rijeka (at the coast) and in Osijek (inland) in June, September and December 1997 and in January and March 1998. Samples were frozen until analysed by HPLC. The highest frequency of samples with concentration >1 ng OTA/ml as well as the highest mean concentration (0.68 ng/ml of plasma) was found in Osijek in June. In Osijek the lowest frequency of OTA-positive samples (48 %) and the lowest mean OTA concentration (0.28 ng/ml) were found in December. In Rijeka the lowest frequency of positive samples (2 %) and the lowest mean concentration (0.05 ng/ml) were found in September. In Osijek and Rijeka the mean concentration of OTA in January (0.49 and 0.36 ng/ml, respectively) was higher than in December (0.28 and 0.19 ng OTA/ml). In Osijek and Rijeka the daily intake of OTA calculated from the mean concentration (0.54 and 0.18 ng OTA/ml, respectively) was 0.72 and 0.24 ng OTA/kg b.w., respectively, which is much lower than tolerable daily intake proposed by World Health Organization (16.0 ng/kg).

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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