Pregled bibliografske jedinice broj: 724646
Development and validation of LC-MS/MS method for quantification of opiorphin in human saliva
Development and validation of LC-MS/MS method for quantification of opiorphin in human saliva // Book of abstracts of the 13th International Chromatography School
Zagreb, Hrvatska, 2012. str. 48-48 (poster, međunarodna recenzija, sažetak, stručni)
CROSBI ID: 724646 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Development and validation of LC-MS/MS method for quantification of opiorphin in human saliva
Autori
Brkljačić Lidija ; Sabalić, Maja ; Salarić, Ivan ; Jerić, Ivanka ; Alajbeg, Ivan ; Nemet, Ina
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Izvornik
Book of abstracts of the 13th International Chromatography School
/ - , 2012, 48-48
Skup
13th International Chromatography School
Mjesto i datum
Zagreb, Hrvatska, 19.06.2012. - 20.06.2012
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Opiorfin ; LC-ESI-MS/MS ; Slina
(Opiorphin ; LC-ESI-MS/MS ; Saliva)
Sažetak
Using opiorphin as a potential biomarker of different pathological states requires the development of robust and sensitive methods. We developed a highly sensitive and specific liquid chromatography with tandem mass spectrometric detection (LC–ESI–MS/MS) analytical method for the analysis of opiorphin in human saliva with limited sample manipulation. The analytical method for determination of opiorphin in the human saliva was also validated on the following parameters: linearity, limit of detection (LOD), lower limit of quantification (LLOQ), precision, accuracy, recovery, matrix effect and sample stability.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Temeljne medicinske znanosti, Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Stomatološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Klinička bolnica "Dubrava",
Sveučilište u Zagrebu
