Pregled bibliografske jedinice broj: 722787
Ejecting phage DNA against cellular turgor pressure
Ejecting phage DNA against cellular turgor pressure // Biophysical journal, 107 (2014), 8; 1924-1929 doi:10.1016/j.bpj.2014.09.002 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 722787 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Ejecting phage DNA against cellular turgor pressure
Autori
Marion, Sanjin ; Šiber, Antonio
Izvornik
Biophysical journal (0006-3495) 107
(2014), 8;
1924-1929
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
bacteriophage; DNA ejection; in vivo
Sažetak
We examine in vivo ejection of noncondensed DNA from tailed bacteriophages into bacteria. The ejection is dominantly governed by the physical conditions in the bacteria. The confinement of the DNA in the virus capsid only slightly helps the ejection, becoming completely irrelevant during its last stages. A simple calculation based on the premise of condensed DNA in the cell enables us to estimate the maximal bacterial turgor pressure against which the ejection can still be fully realized. The calculated pressure (∼5 atm) shows that the ejection of DNA into Gram-negative bacteria could proceed spontaneously, i.e., without the need to invoke active mechanisms.
Izvorni jezik
Engleski
Znanstvena područja
Fizika
POVEZANOST RADA
Projekti:
035-0352828-2837 - Energetskom kompeticijom uvjetovani oblici i strukture nanometarskih sustava (Šiber, Antonio, MZOS ) ( CroRIS)
Ustanove:
Institut za fiziku, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE