Naslov
Placenta growth factor in healthy and diabetic mothers and their fetuses

Autori
Đelmiš, Josip ; Ivanišević, Marina ; Mayer, Davor ; Tuzović, Lea ; Starčević, Vito ; Ilijić, Marcela

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni

Knjiga
Perinatology 2001

Urednik/ci
Cabero, Luis ; Carrera, Jose Ma.

Izdavač
Monduzzi Editore

Grad
Bolonja

Godina
2001

Raspon stranica
671-674

ISBN
Undefined

Ključne riječi
PIGF, angiogenesis, diabetic pregnancy

Sažetak
Angiogenesis and vascular transformation are important processes in the normal development of the placenta. Placenta growth factor (PlGF) is a potent angiogenic growth factor and it is important for placental development. Serum samples were collected from (1) 56 healthy pregnant women during pregnancy and umbilical vein at the time of delivery and (2) 123 diabetic pregnant women during pregnancy and umbilical vein at the time of delivery. There was no significant difference between the groups in maternal age or gestational age. PlGF in healthy pregnant women at the time of delivery was lower (194,9ą24,8 pg/mL) than in diabetic women (217,5ą17,4 pg/mL). Significant coefficient correlations between level of PlGF in serum of umbilical vein and newborn weight (r=0,4), placental weight (r=0,6), and erythropoetin (r= -0,3) were found. Fetal umbilical vein serum levels of PlGF correlate with maternal serum levels (r=0,35).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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