Naslov
Honeydew honey as a potential agent against drug - resistant bacteria

Autori
Crnković, Goranka ; Knapić, Matea ; Babić, Ana ; Malenica Staver, Mladenka ; Lušić, Dražen ; Gobin, Ivana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of abstracts of the International Symposium on Bee Products 3rd edition - Annual meeting of the International Honey Commission (IHC) / Brčić Karačonji, Irena ; Dražen, Lušić - Rijeka, 2014, 111-111

ISBN
978-953-7957-26-1

Skup
International Symposium on Bee products, Annual meeting of the International Honey Commission (IHC)

Mjesto i datum
Opatija, Hrvatska, 28.09.2014. - 01.10.2014

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
honeydew; antibacterial effect; drug – resistant bacteria; therapy

Sažetak
Strains of methicillin-resistant Staphylococcus aureus and multidrug-resistant Acinetobacter baumannii have become increasingly common and the spread of these represents a serious health threat. Since ancient times, honey has been known to possess antimicrobial properties. The objectives of this study were to test the antibacterial activity of honeydew honey against drug resistant A. baumannii and S. aureus. Using a broth dilution method, the antibacterial activity of 7 different type of honeydew honey, 6 samples of fir honeydew – Abies alba Mill and maple honeydew (Acer spp., chestnut – Castanea sativa Mill), against multi-drug resistant and drug sensitive strains of A. baumannii and S. aureus was determined. Different concentrations of honey (0, 025 g/ml – 0, 4 g/ml) were tested against each bacterial strain. The minimum inhibitory concentration (MIC) were determined by visual inspection as the lack of visual turbidity and minimum bactericidal concentration (MBC) also was determined by culturing on blood agar plates. Our result showed that all tested A. baumannii and S. aureus strains were sensitive to fir honeydew regardless of the resistance. The lowest MIC value of 0, 025 g/ml and MBC value of 0, 05 g/mL for fir honeydew honeys was against multi-drug resistant A. baumannii as well as MRSA. In summary, we showed that fir honeydew possesses strong bactericidal activity against drug resistant bacteria, A. baumannii and S. aureus. Thus, this honey has excellent potential as an anti-infective agent for infections caused by antibiotic-susceptible or -resistant bacteria. However, this approach needs to be further studied.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Biotehnologija

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