Naslov
Synthesis and spectroscopic studies of some quinoline-based dialkyl alpha-aminophosphonates

Autori
Tušek-Božić, Ljerka ; Komac, Marijana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
ESOR-8 Programme and Abstracts / Eckert-Maksić, M. ; Glasovac, Z. ; Zrinski, I. - Zagreb : Institut Ruđer Bošković, 2001, 239-239

Skup
8th European Symposium on Organic Reactivity

Mjesto i datum
Dubrovnik, Hrvatska; Cavtat, Hrvatska, 01.09.2001. - 06.09.2001

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
synthesis; aminophosphonate; spectroscopy

Sažetak
In attempts to find new bioactive phosphonates with suitable ligand properties, we develop a convenient and efficient method for the preparation of two types of quinoline-based dialkyl alpha-aminophosphonates ; those of [alpha-anilino-(2-quinolylmethyl)]phosphonic acid (type A) and [alpha-(3-quinolylamino)-N-benzyl]phosphonic acid (type B). Reaction of an equimolar amount of appropriate aldehyde and amine gave the corresponding Schiff base, which by addition of dialkyl phosphite afforded formation of dialkyl phosphonates. Individual steps, condensation reaction and phosphite addition, were examined by IR and NMR spectroscopy.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA