Naslov
Chirality induction in ML2 metal complexes with amino acid substituted bis(2-picolyl)amine ligands

Autori
Sanders, Ernest ; Škalamera, Đani ; Vianello, Robert ; Pevec, Andrej ; Turel, Iztok ; Kirin, Srećko I.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts / Dr. Daniela Donghi - Zürich, 2014, 74-74

Skup
2nd Symposium on Functional Metal Complexes that Bind to Biomolecules

Mjesto i datum
Zürich, Švicarska, 22.08.2014. - 23.08.2014

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
metalni kompleksi; biokonjugati; aminokisline; dušikovi ligandi
(metal complexes; bioconjugates; amino acids; nitrogen ligands)

Sažetak
Metal complexes of tridentate ligands L with ML2 stoichiometry can form several six-coordinated geometrical isomers: meridional, trans-facial, and delta or lambda cis-facial. For the rigid terpyridyne ligand (L = terpy), the meridional isomer of the corresponding M(terpy)2 metal complexes is strongly preferred, while complexes with the more flexible bis(2-picolyl)amine ligand (L = bpa) could form both meridional and facial isomers. Interestingly, however, all reported single crystal structures M(R-bpa)2 complexes with substituents R ≠ H reveal only cis-facial geometry, even with very bulky substituents where a trans-geometry might be expected due to sterical hindrance. Continuing our interest in metal complexes with nitrogen ligand amino acid bioconjugates, we present herein the synthesis and characterization of L1 – L5 and their ML or ML2 complexes with M = Zn(II), Co(II) or Ni(II). Particular attention will be paid to possible inter-strand hydrogen bonding and chirality induction in the ML2 complexes.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA