Naslov
Spectrophotometric studies of novel derivatives of vitamin B6

Autori
Gašo-Sokač, Dajana ; Bušić, Valentina ; Habuda-Stanić, Mirna ; Nujić, Marija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
15. Ružička days "Today Science - Tomorrow Industry" / Šubarić, Drago - Osijek : Grafika Osijek, 2014, 31-31

ISBN
978-953-7005-34-4

Skup
International Scientific and Professional Conference 15th Ružička days

Mjesto i datum
Vukovar, Hrvatska, 11.09.2014. - 12.09.2014

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
derivatives of vitamin B6; UV-VIS spectroscopy

Sažetak
Chemistry of vitamin B6 was intensively investigated for nearly a century, which is understandable given the importance of the life processes in the body. In recent years research has focused on the synthesis and spectroscopic studies of new analogs of vitamin B6, which can be used in human medicine for recovery of the organism poisoning by organophosphorus compounds. UV/VIS absorption spectra of the synthesized derivatives of vitamin B6 were recorded in aqueous solutions of different pH values. Spectra were recorded on Specord 200 spectrophotometer (Analytik Jena AG) at a temperature of 25 °C. pH readings were fitted using the appropriate amount of hydrochloric acid (0.2 M), sodium hydroxide (0.2 M) and Britton-Robinson buffer. Britton-Robinson buffer was prepared by mixing equimolar amounts of phosphorous (0.04 M H3PO4) acetate (0.04 M CH3COOH) and boric acid (0.04 M H3BO3). Absorption spectra of aqueous solutions of the test compounds changed with changing the pH of the solution. In acidic medium there are two peaks, one at about 280-293 nm and the other at 330 nm. By increasing the pH the second peak is lost, and the first moves at about 270-274 nm with the emergence of a new peak at about 378-380 nm.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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