Naslov
Exercise before SCUBA diving ameliorates decompression- induced neutrophil activation

Autori
Madden, Dennis ; Thom, Stephen R. ; Milovanova, Tatyana N. ; Yang, Ming ; Bhopale, Veena M. ; Ljubković, Marko ; Dujić, Željko ;

Izvornik
Medicine and science in sports and exercise (0195-9131) 46 (2014), 10; 1928-1935

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
scuba diving ; microparticles ; decompression

Sažetak
INTRODUCTION: The goals of this study were to investigate the difference in responses between a SCUBA dive preceded by aerobic exercise (EX) and a non-exercise control dive (CON), and further evaluate the potential relationship between venous gas emboli (VGE) and microparticles (MP). We hypothesized that exercise would alter the quantity and subtype of annexin V- positive MPs and VGE. METHODS: Nineteen divers performed 2 dives to 18 m sea water for 41 min separated by at least 3 days, one of which was preceded by 60 min of treadmill interval exercise. Blood was obtained before exercise, before diving, and 15 min, 2, 4, and 24 h after surfacing. Intravascular bubbles were quantified by transthoracic echocardiography at 15, 40, 80, and 120 min. RESULTS: The median VGE remained unchanged between the 2 dives ; however, there was a significant increase in VGE in the exercise dive at 40 and 80 min at rest. MPs were significantly elevated by approximately 2x at all time points following CON compared to EX. Markers of neutrophil and platelet activation were elevated by both dives and these elevations were attenuated in the EX dive. CONCLUSIONS: We conclude that some of the differences observed between the EX and CON related to MPs, platelet, and neutrophil activation provide additional insight to the potential protective benefits of exercise, however, further study is needed to understand the mechanism and true potential of these benefits.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA