Naslov
Epigenetic regulation of fetal brain development and neurocognitive outcome

Autori
Petanjek, Zdravko ; Kostović, Ivica

Izvornik
Proceedings of the National Academy of Sciences of the United States of America (0027-8424) 109 (2012), 28; 11062-11063

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
schizophrenia; hypoxia; infection; fetal injury

Sažetak
Twenty-five years ago, the neurodevelopmental hypothesis of schizophrenia opened the way for analyzing potential prenatal influences on late postnatal pathogenetic events (1). Since that time, it has been well-established that hypoxia, infection, and other noxious factors can cause fetal brain injury and intrauterine growth restriction and that prenatal brain lesions can cause alterations in the postnatal brain development (2). A study in PNAS (3) suggests that even the subtle normal variations of intrauterine environment may lead to recognizable differences in postnatal brain structure and cognitive functions. Raznahan

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA