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Pregled bibliografske jedinice broj: 711333

Changes in cAMP levels in the developing opossum spinal cord at the time when regeneration stops being possible.


Mladinić, Miranda
Changes in cAMP levels in the developing opossum spinal cord at the time when regeneration stops being possible. // Cellular and molecular neurobiology, 27 (2007), 7; 883-888 doi:10.1007/s10571-007-9208-3 (međunarodna recenzija, kratko priopcenje, znanstveni)


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Naslov
Changes in cAMP levels in the developing opossum spinal cord at the time when regeneration stops being possible.

Autori
Mladinić, Miranda

Izvornik
Cellular and molecular neurobiology (0272-4340) 27 (2007), 7; 883-888

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
Spinal cord Opossum cAMP Regeneration Development

Sažetak
Cyclic AMP (cAMP) is an important second messenger in signaling pathways that regulate cellular processes involved in development and regeneration. The changes in cAMP content of opossum spinal cords have been studied during the critical period of development, when the ability to regenerate axons after injury is lost. Endogenous cAMP levels were measured in tissue homogenates, and cAMP immunoreactivity was displayed in sections of lesioned and non- lesioned opossum P6 (can regenerate) and P13 (cannot regenerate) spinal cords. There was a significant decrease of the cAMP levels during the period critical for regeneration, while the level of cAMP was increased in P6 spinal cords after injury. Moreover, 5 mM db-cAMP induced growth in vitro of the injured axons in the spinal cord that has lost the capacity to regenerate.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Ustanove:
Sveučilište u Rijeci - Odjel za biotehnologiju

Poveznice na cjeloviti tekst rada:

doi link.springer.com

Citiraj ovu publikaciju:

Mladinić, Miranda
Changes in cAMP levels in the developing opossum spinal cord at the time when regeneration stops being possible. // Cellular and molecular neurobiology, 27 (2007), 7; 883-888 doi:10.1007/s10571-007-9208-3 (međunarodna recenzija, kratko priopcenje, znanstveni)
Mladinić, M. (2007) Changes in cAMP levels in the developing opossum spinal cord at the time when regeneration stops being possible.. Cellular and molecular neurobiology, 27 (7), 883-888 doi:10.1007/s10571-007-9208-3.
@article{article, author = {Mladini\'{c}, Miranda}, year = {2007}, pages = {883-888}, DOI = {10.1007/s10571-007-9208-3}, keywords = {Spinal cord Opossum cAMP Regeneration Development}, journal = {Cellular and molecular neurobiology}, doi = {10.1007/s10571-007-9208-3}, volume = {27}, number = {7}, issn = {0272-4340}, title = {Changes in cAMP levels in the developing opossum spinal cord at the time when regeneration stops being possible.}, keyword = {Spinal cord Opossum cAMP Regeneration Development} }
@article{article, author = {Mladini\'{c}, Miranda}, year = {2007}, pages = {883-888}, DOI = {10.1007/s10571-007-9208-3}, keywords = {Spinal cord Opossum cAMP Regeneration Development}, journal = {Cellular and molecular neurobiology}, doi = {10.1007/s10571-007-9208-3}, volume = {27}, number = {7}, issn = {0272-4340}, title = {Changes in cAMP levels in the developing opossum spinal cord at the time when regeneration stops being possible.}, keyword = {Spinal cord Opossum cAMP Regeneration Development} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





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