Naslov
The role of GABA in development and behaviour: emphasize on the effects of GABA receptor agonists and antagonists

Autori
Jazvinšćak Jembrek, Maja ; Vlainić, Josipa ; Radovanović, Vedrana

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni

Knjiga
Gamma-aminobutyric Acid (GABA): biosynthesis, medicinal uses and health effects

Urednik/ci
Vlainić, Josipa ; Jazvinšćak Jembrek, Maja

Izdavač
Nova Science Publishers

Grad
New York (NY)

Godina
2014

Raspon stranica
49-70

ISBN
978-1-63321-838-3

Ključne riječi
GABA ; development ; circadian rhythms ; sleep ; feeding ; aggressive behavior ; learning and memory

Sažetak
Normal brain functioning is characterized by the balance between excitatory and inhibitory neurotransmission. Gamma-aminobutyric acid (GABA) acts as the major inhibitory neurotransmitter in the mammalian brain and is found throughout the central nervous system. Ionotropic GABA-A/C and metabotropic GABA-B receptors that mediate effects of GABA are also extensively distributed in the brain. GABA affects numerous physiological processes. This review will briefly summarize some of the major functions of GABA, including the role of GABA in development and brain masculinization, and effects of GABA on circadian rhythms, sleep, feeding, aggressive behavior, and learning and memory, mostly deduced from the studies using GABA receptor agonists and antagonists.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA