Naslov
Impact of mothers nutrition and nutrition of offspring on spontaneous physical activity in male offspring

Autori
Perić Kačarević, Željka ; Marić, Anđela ; Vrselja, Zvonimir ; Čekić, Nenad ; Radić, Radivoje

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Obesity Facts / Johannes Hebebrand - Ettlingen : Karger Publishers, 2014, 118-118

ISBN
978-3-318-02707-5

Skup
21st European Congress on Obesity

Mjesto i datum
Sofija, Bugarska, 28.05.2014. - 31.05.2014

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
obesity; high-fat diet; physical activity

Sažetak
Introduction: Few studies have addressed the potential role of changes in energy expenditure, precisely in spontaneous physical activity (SPA) which accompanies nonexercise activity thermogenesis (NEAT), in mediating the resistance to fat gain. The aim of the study is to determine the effect of maternal diet on the role of spontaneous physical activity to modulate effects of development obesity in male offspring. Methods: Ten female Sprague Dawley rats were randomly divided in two groups at the age of 21 days, one was fed high-fat diet (HFD), the other one with standard laboratory chow (CD). At the age of 12 weeks, the rats were mated, and their offspring were also randomly dived in HFD and CD group after the lactation period. We measured body weight and at the 11 weeks old rat’s movements were measurement using Activity Cage. Results: HFD-CD and CD-HFD groups had the lowest weight after birth, but their weight increased the most compared to CD-CD and HFD-HFD rats. The statistical difference in weight among groups was found only between CD-CD and HFD-CD group, with CD-CD group being heavier (430 ± 24 vs. 384 ± 24 ; p = 0.002). HFD-CD had more horizontal spontaneous movements then other three groups. CD-HFD and HFD-CD had more vertical spontaneous movements then other two groups (CD-CD and HFD-HFD). Conclusion: CD-HFD and HFD-CD rats had highest SPA and highest weight gain. As energy intake exceeded energy expenditure the system responded by increasing energy expenditure. Changes in diet influenced the changes in SPA which predicted resistance to fat gain with overfeeding.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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