Naslov
Non-Alcoholic Fatty Liver Disease Proven by Transient Elastography in Hemodialysis Patients: Is It a New Risk Factor for Adverse Cardiovascular Events?

Autori
Mikolašević, Ivana ; Rački, Sanjin ; Lukenda, Vesna ; Milić, Sandra ; Devčić, Bosiljka ; Orlić, Lidija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Nephrology Dialysis Transplantation (NDT)2014 ; 29(Suppl.3):iii233 / Pieter M. ter Wee - : Oxford University Press, 2014, Iii233-iii233

Skup
51st ERA-EDTA Congress

Mjesto i datum
Amsterdam, Nizozemska, 31.05.2014. - 03.06.2014

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Cardiovascular disease; Hemodialysis; Non-alcoholic fatty liver disease; Transient elastography

Sažetak
Background/Aims: Cardiovascular diseases (CVD) are the leading cause of mortality in hemodialysis (HD) patients. Recently, non-alcoholic fatty liver disease (NAFLD) has been recognized as a new risk factor for adverse CVD events in the general population. Our aim was to analyze the incidence of NAFLD in HD patients by using transient elastography and to analyze whether the presence of NAFLD is associated with a higher CVD risk in HD patients. Methods: The subjects were 72 HD patients and 50 sex- and age-matched controls. Results: NAFLD was found in 52.8% of HD patients. HD patients with NAFLD showed more carotid atherosclerosis and more adverse CVD events than HD patients without NAFLD andcontrol subjects. Conclusion: We showed for the first time that HD patients have a high prevalence of NAFLD. HD patients with NAFLD show an advanced carotid atherosclerosis. Detection of NAFLD by transient elastography should alert to the existence of an increased cardiovascular risk in HD patients.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA