Naslov
Predictive value of surveillance cultures for septic shock in patients with abdominal surgical condition

Autori
Mazul Sunko, Branka ; Perić, Mladen ; Kolak, Josip ; Vučić, Marinko ; Genter, Ivan ; Jajić Benčić, Ines ; Rajić, B.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of 14th annual Congress of European society of intensive care medicine, u: Intensive Care Med 2001 ; 27(suppl.2):S204 / - Ženeva, 2001, S204-S204

Skup
14th Annual Congress of European Society of intensive care medicine

Mjesto i datum
Ženeva, Švicarska, 30.09.2001. - 03.10.2001

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
surveillance culture ; predictive value ; septic shock

Sažetak
Introduction. We investigated correlation of nasal and perianum surveillance cultures with septic shock. Methods. We analysed nasal and perianum surveillance cultures in three groups of patients with surgical abdominal illness. Group 1 (n=13) were patients with septic shock. Septic shock was defined as hypotension associated with sepsis, with blood pressure <90mmHg or reduction >= 40 mmHg from baseline in absence of hypovolemia and heart failure. Group 2 (n=12) were septic patients defined as patients with positive SIRS andmicrobiological finding., or otherwise proven focus of infection. Group 3 (n=40) was a control group of randomly chosen patients with similar abdominal surgical pathology admitted to ICU, who developed neither sepsis nor septic shock. There was no difference in demographic data among the groups. At admittance to ICU, nasal and perianum surveillance cultures were taken, as well as standard biochemical tests. General condition of patients was assessed using three clinical scoring systems: MODS, SIRS and APACHE II. Only data taken on the first day in the ICU were analysed. Results. Chi-square test was used for analysis of non-continuous data, and Mann-Whitney U test for continuous ones with non-Gaussian distribution. There is a significant correlation between Candida species in nasal surveillance culture (p=0.015) and Pseudomonas aeruginosa in perianum culture (p=0.004) with septic shock. Patients with septic shock differed from the control group in APACHE II score (p=0.001) and MODS (p=0.019), but not SIRS. As forbichemical data, there is a difference between septic shock and control groups in fibrinogen level (p=0.0003). At III concentration (p=0.016) and white blood cell count (p=0.0002). There is no difference in any of these vriables between non-shock septic patients and controls. Conclusion. The presence of Candida sp. in nasal and pseudomonas aeruginosa in perianum surveillance culture are predictive of septic shock in this group of abdominal surgical patients.General condition of patients assessed through APACHE II and MODS is another predictive factor. Among biochemical data, white blood cell count, fibrinogen level and AT III are of prognostic value.

Izvorni jezik
Engleski

Napomena
U: Abstracts, 14th annual congress of European Society of intensive care medicine.

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