Naslov
Electrophysiological and regional cerebral blood flow correlation in schizophrenic patients after substitution of haloperidol by risperidone

Autori
Divošević, Sunčana ; Petrović, Ratimir ; Šain, Ivica ; Medved, Vesna ; Poropat, Mirjana ; Dodig, Damir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Journal of Nuclear Medicine and Molecular Imaging / - Berlin : Springer, 2004, S372-S373

Skup
Annual Congress of the European Association of Nuclear Medicine

Mjesto i datum
Helsinki, Finska, 04.09.2004. - 08.09.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
regional cerebral blood flow (rCBF); single photon emission computed tomography (SPECT); schizophrenia; haloperidol; risperidone; P 300 auditory event-related potential components (ERPs)

Sažetak
This study examined the relationship of rCBF and P 300 ERPs in 13 schizoprenic female patients treated with haloperidol after being replaced by risperidone. The co-occurence of rCBF, clinical and electrophysiological improvements serve as a powerfull indicator of cognitive function and risperidone effectiveness, having a greater beneficial influence on neurocognition compared to conventional antipsychotics, also helping in understanding the pathophysiology of schizophrenia and encouraging the use of SPECT for individual estimation of different antipsychotic effects.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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