Naslov
Model of Aneurysmal Enlargement Based on Biochemomechanical Processes in Intraluminal Thrombus

Autori
Virag, Lana ; Wilson, John S. ; Vindiš, Vedran ; Karšaj, Igor ; Humphrey, Jay D.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
Multiscale Methods and Validation in Medicine and Biology II: Biomechanics and Mechanobiology

Mjesto i datum
Berkeley (CA), Sjedinjene Američke Države, 13.02.2014. - 14.02.2014

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Abdominal aortic aneurysm; intraluminal thrombus; growth & remodeling

Sažetak
Abdominal aortic aneurysm (AAA) is a dilatation of a blood vessel due to irreversible pathological remodeling of the extracellular matrix. Majority of AAAs include intraluminal thrombus (ILT). These thrombi have complex natural histories and structures, and their biological and mechanical properties influence growth and remodeling (G&R) of AAAs. Numerous studies were conducted to investigate if ILT can change stress distribution in aortic wall. Recently, there is also increasing evidence that ILT is biologically active and should not be treated as homogeneous inert material. We present you the first attempt to comprehensively model G&R of the thrombus-laden AAAs.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA