Pregled bibliografske jedinice broj: 696207
Laccase Inhibiting Activity of Some Coumarin Derivatives
Laccase Inhibiting Activity of Some Coumarin Derivatives // Letters in organic chemistry, 11 (2014), 8; 583-589 (međunarodna recenzija, članak, znanstveni)
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Naslov
Laccase Inhibiting Activity of Some Coumarin Derivatives
Autori
Tišma, Marina ; Molnar, Maja ; Škarica, Marija ; Čačić, Milan ; Zelić, Bruno
Izvornik
Letters in organic chemistry (1570-1786) 11
(2014), 8;
583-589
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
coumarins; laccase activity; inhibition; ABTS; L-DOPA.
Sažetak
Seven coumarin derivatives were screened for their inhibitory effect on laccase utilizing ABTS and L- DOPA as substrates. 2-[(4-Methyl-2-oxo-2H-1- benzopyran-7-yl)oxy]acetic acid (E)-2- [(dihydroxyphenyl)methylene]hydrazides were proven to be stronger inhibitors than corresponding thiosemicarbazides when ABTS [2, 2'-azinobis(3- ethylbenzothiazoline-6-sulfonic acid)] was used as a substrate. In kinetic experiments mixed type inhibition was determined for 2-[(4-methyl-2-oxo- 2H-1-benzopyran-7-yl)oxy]acetic acid (E)-2-[(2, 5- dihydroxyphenyl)methylene]hydrazide and (E)-2- [(3, 4-dihydroxyphenyl)methylene]hydrazide. In reaction of L-DOPA (L-3, 4-dihydroxyphenylalanine) oxidation catalyzed by laccase none of the tested compounds has shown inhibitory effect.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Biotehnologija
POVEZANOST RADA
Ustanove:
Prehrambeno-tehnološki fakultet, Osijek,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
