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Pregled bibliografske jedinice broj: 695517

The anticancerogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.)

Kulišić-Bilušić, Tea; Schmöller, I.; Schnäbele, K.; Siracusa, L.; Ruberto, G.
The anticancerogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.) // Food chemistry, 132 (2012), 1; 261-267 doi:10.1016/j.foodchem.2011.10.074 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 695517 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
The anticancerogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.)

Autori
Kulišić-Bilušić, Tea ; Schmöller, I. ; Schnäbele, K. ; Siracusa, L. ; Ruberto, G.

Izvornik
Food chemistry (0308-8146) 132 (2012), 1; 261-267

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Caper Essential oil; aqueous infusion; anticancer activity; cell cycle; NF-jB activity; HT-29 cells

Sažetak
The present study assessed the influence of essential oil and aqueous infusion from wild-grown caper(Capparis spinosa L.) on cell growth, NF-jB activation, apoptosis and cell cycle in the human colon carcinoma cell line, HT-29. Methyl isothiocyanate (92.06%), a degradation product of glucosinolate glucocapparin, was detected as major component of essential oil from caper leaves and flower buds. Aqueous infusion of caper showed an interesting and variegate compositional pattern containing several phenolic compounds, among which a flavonol glycoside, rutin (quercetin 3-O-rutinoside, 50.7%) and 5-caffeoylquinic acid (chlorogenic acid, 17.5%) were detected as dominant. Caper essential oil and aqueous infusion showed time- and dose-dependent high inhibitory effect on HT-29 cell proliferation. In addition, they induced the inhibition on nuclear factor jB (NF-jB) activity in a dose-dependent manner, while they did not show any effect on apoptosis in HT-29 cells. Flow cytometric analysis indicated that treatment with caper essential oil and aqueous infusion resulted in G2/M cell cycle arrest in a dose-dependent manner.Presented results suggest that caper contains volatile and non-volatile compounds which potentially can play an important role in colon cancer prevention.

Izvorni jezik
Engleski

Znanstvena područja
Prehrambena tehnologija



POVEZANOST RADA

Ustanove:
Kemijsko-tehnološki fakultet, Split

Profili:

Avatar Url Tea Bilušić (autor)

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com

Citiraj ovu publikaciju:

Kulišić-Bilušić, Tea; Schmöller, I.; Schnäbele, K.; Siracusa, L.; Ruberto, G.
The anticancerogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.) // Food chemistry, 132 (2012), 1; 261-267 doi:10.1016/j.foodchem.2011.10.074 (međunarodna recenzija, članak, znanstveni)
Kulišić-Bilušić, T., Schmöller, I., Schnäbele, K., Siracusa, L. & Ruberto, G. (2012) The anticancerogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.). Food chemistry, 132 (1), 261-267 doi:10.1016/j.foodchem.2011.10.074.
@article{article, author = {Kuli\v{s}i\'{c}-Bilu\v{s}i\'{c}, Tea and Schm\"{o}ller, I. and Schn\"{a}bele, K. and Siracusa, L. and Ruberto, G.}, year = {2012}, pages = {261-267}, DOI = {10.1016/j.foodchem.2011.10.074}, keywords = {Caper Essential oil, aqueous infusion, anticancer activity, cell cycle, NF-jB activity, HT-29 cells}, journal = {Food chemistry}, doi = {10.1016/j.foodchem.2011.10.074}, volume = {132}, number = {1}, issn = {0308-8146}, title = {The anticancerogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.)}, keyword = {Caper Essential oil, aqueous infusion, anticancer activity, cell cycle, NF-jB activity, HT-29 cells} }
@article{article, author = {Kuli\v{s}i\'{c}-Bilu\v{s}i\'{c}, Tea and Schm\"{o}ller, I. and Schn\"{a}bele, K. and Siracusa, L. and Ruberto, G.}, year = {2012}, pages = {261-267}, DOI = {10.1016/j.foodchem.2011.10.074}, keywords = {Caper Essential oil, aqueous infusion, anticancer activity, cell cycle, NF-jB activity, HT-29 cells}, journal = {Food chemistry}, doi = {10.1016/j.foodchem.2011.10.074}, volume = {132}, number = {1}, issn = {0308-8146}, title = {The anticancerogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.)}, keyword = {Caper Essential oil, aqueous infusion, anticancer activity, cell cycle, NF-jB activity, HT-29 cells} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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