Naslov
Diagnostic value of overnight polysomnography in epileptic patients with nocturnal epileptic attacks with special reference to sleep structure

Autori
Detoni, Josip ; Pavliček, Ivan ; Dobec-Gorenak, Dubravka ; Kostanjevec, Ruža ; Pintarec, Tihomir ; Dvorski, Marija

Izvornik
Neurologia Croatica (0353-8842) 47 (1998), 1; 17-26

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Epilepsy; Polymnography; Sleep

Sažetak
Overnight polysomnography was performed in a group of 27 subjects, 13 men and 14 women, mean age 32.63±11.42 years, who manifested epileptic attacks during sleep and had normal or suspect findings in wakefulness. EEG characteristics recorded in wakefulness were designated as normal, borderline or nonspecific dysrhythmic changes in 29.63 % of the subjects. EEG characteristics recorded during overnight polysomnography were designated as focal dysrhythmic in 18.52 %, generalized paroxysmal in 51.85 %, and both types of changes occurring simultaneously in 18.52 % of the subjects. Thus, EEG changes specific and characteristic of epileptic etiology were manifested in sleep by 88.89 % of the subjects. Focal EEG discharges were most commonly recorded in the superficial stages of NREM sleep (50 %), followed by REM sleep (25 %) and wakefulness after overnight sleep (18.75 %). Generalized paroxysmal EEG discharges were grossly present in the superficial NREM stages (69.24 %) and residually in REM sleep (15.3 %). Thus, generalized discharges and to a lesser extent focal ones, are strongly facilitated by NREM stages, this effect being inversely proportional to the sleep depth. Focal discharges are facilitated by REM stage, whereas generalized discharges are only residually present in this phase of sleep. Sleep disturbances were recorded in 55.56 %, REM suppression in 18.52 %, and suppression of slow wave sleep, unspecific sleep disorders and fragmented sleep together in 37.04 % of the subjects with nocturnal epileptic attacks. The subjects exhibiting generalized paroxysmal dysrhythmic EEG changes in sleep showed a considerably higher proportion of REM suppression (35.71 %), indicating that these specific changes might play a role in the suppression of REM sleep.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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