Naslov
Deep brain stimulation for the early treatment of the minimal consciousness state and vegetative state.

Autori
Chudy, Darko ; Deletis, Vedran ; Rogic, Maja, Paradzik, Veronika ; Grahovac Gordan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Stereotact Funct Neurosurg ; 90 (suppl 1): 1-202 / António J. Gonçalves Ferreira, Lisbon Joachim K. Krauss, Hannover Bart Nuttin, Leuven Jean Régis, Marseille Damianos Sakas, Athens Rick Schuurman, Amsterdam - Basel : Karger Publishers, 2012, 1-202

ISBN
9783318022599

Skup
Stereotactic and Funcnional Neurosurgery XXth Congress of the European Society for Stereotactic and Functional Neurosurgery

Mjesto i datum
Lisabon, Portugal; Cascais, Portugal, 26.09.2012. - 29.09.2012

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Deep brain stimulation; minimal consciousness state

Sažetak
Introduction: To present results of DBS for the early treatment of minimal consciousness state (MCS) and vegetative state (VS) caused by hypoxic encephalopathy or traumatic brain injury in eleven patients. Methods: Eleven patients were evaluated neurologically and electrophysiologically for possible treatment with deep brain stimulation. Among these patients, seven patients were in vegetative state and four patients were in minimal consciousness state. The stimulation sites in all patients were centromedian-parafascicular nucleus complex. Somatosensory, motor and brain stem auditory evoked potentials, and 24 hour recordings of EEG were performed before surgery. PET CT was performed before and after DBS implantation. Patients were stimulated during the day for 30 min every three hours with different intensity and frequency parameters. Results: Two patients in MCS regained consciousness, independent walking without help, become able to speak, showing impressive speech comprehension, but needed some assistance with their everyday life. Other nine patients remained bedridden and their status remained unchanged but showed improvement in Rappaport Coma/Near coma scale. Conclusion: The DBS is not yet “evidence-based treatment” of the vegetative and MCS. This report shows that if the patient fulfills neurophysiologic, PET and clinical criteria he should be treated with DBS at the very early stage of MCS.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA