Naslov
Deep brain stimulation for early treatment of the minimal consciousness state: case report. A case report.

Autori
Chudy, Darko ; Deletis Vedran ; Grahovac, Gordan ; Almahariq, Fadi ; Rogić, Maja ; Tudor, Katarina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Acta Clinica Croatica, 6 th Congress of the Croatian Neurosurgical Society and the Joint Meeting with the Slovenian Neurosurgical Society / Sestre milosrdnice University Hospital and Institute of clinical Medical Research - Zagreb, 2011, 73-73

Skup
6 th Congress of the Croatian Neurosurgical Society and the Joint Meeting with the Slovenian Neurosurgical Society

Mjesto i datum
Opatija, Hrvatska, 25.05.2011. - 28.05.2011

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
deep brain stimulation; minimal consciousness state

Sažetak
Aim: To present results of DBS for the early treatment of minimal consciousness state (MCS) caused by hypoxic encephalopathy. Methods: 17 years old boy sustained cardiac arrest on 16th of Nov 2010 with a subsequent coma for a month, myoclonisms of trunk and head, following by MCS for three months before DBS. Somatosensory, motor and brain stem auditory evoked potentials were within normal limits. 24 hour recordings of EEG showed dominant alpha/theta activity with occasional pronounced beta bursts during the night. PET showed globally reduced glucoses metabolism at the cerebral cortex. MRI at the early stage of coma showed lesions in basal ganglia on both sites. At the time of DBS implantation (19th of Jan, 2011) MRI showed enlarged ventricles with diffused brain atrophy. DBS target was left parafascicular nucleus. He was stimulated during the day for 30 min every three hours (intensity 3.2 V, frequency of 25 Hz). Results: One month after surgery the patient regained consciousness, walks with help, receives liquid meals, remained unable to speak, but showing impressive speech comprehension. Myclonisms completely disappeared. After two months he climbs the stairs independently, pronounce simple words, and controls sphincters. Conclusion: The DBS is not yet “evidence-based treatment” of the vegetative and MCS. About 50 patients were treated with DBS but no one in early stage of MCS. This report shows that if the patient fulfills neurophysiologic, PET and clinical criteria he should be treated with DBS at the very early stage of MCS.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

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