Pregled bibliografske jedinice broj: 681848
Neurophysiologic mechanisms of stuttering. Testing of brain motor speech cortical areas (BMSCA) by novel methodology of navigated transcranial magnetic stimulation (nTMS)
Neurophysiologic mechanisms of stuttering. Testing of brain motor speech cortical areas (BMSCA) by novel methodology of navigated transcranial magnetic stimulation (nTMS) // Basic Science and Stuttering: Research for Clinicians, Second Stuttering Symposium at Cavtat, Croatia (2013)
Cavtat, Hrvatska, 2013. (pozvano predavanje, međunarodna recenzija, neobjavljeni rad, znanstveni)
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Naslov
Neurophysiologic mechanisms of stuttering. Testing of brain motor speech cortical areas (BMSCA) by novel methodology of navigated transcranial magnetic stimulation (nTMS)
Autori
Rogić, Maja
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni
Skup
Basic Science and Stuttering: Research for Clinicians, Second Stuttering Symposium at Cavtat, Croatia (2013)
Mjesto i datum
Cavtat, Hrvatska, 26.05.2013. - 29.05.2013
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Mapping primary motor cortex for laryngeal muscles; stuttering
Sažetak
Neurophysiologic mechanisms of stuttering are not completely understood. It has been suggested that the disruptive drive to motor neuron pools involved in speech execution originates from disturbed excitability of brain motor speech cortical areas (BMSCA). Recent studies by transcranial magnetic stimulation (TMS) showed disturbed cortical excitability of primary motor cortex (M1) for tongue and hand muscles. Our group has recently developed specific methodologies for stimulating and recording motor evoked potentials (MEPs) from laryngeal muscles (Deletis et al. 2008 ; Deletis et al. 2009 ; Deletis et al. 2011 ; Espadaler et al. 2012 ; Deletis et al. 2013) as well eliciting transient language disruptions (Rogić et al. 2013). We have also introduced a novel way of the stimulation of BMSCA, using navigated TMS (nTMS) and novel patterned burst of magnetic stimuli. By applying this novel methodological approaches we will be able to measure indexes of motor speech abnormalities for M1 for laryngeal muscle representation in people who stutter (PWS). Neurophysiologic measures of cortical excitability will be obtained by stimulating bilateral motor laryngeal representations respectively and recording MEPs from cricothyroid muscle. Investigation of neurophysiologic mechanisms of stuttering will be the background for: a) Classification of different forms of stuttering on the basis of neurophysiologic profile. b) Development of therapeutic approaches for PWS based on neurophysiologic profile.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti