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Pregled bibliografske jedinice broj: 677346

Toward the practical implementation of eye-related bioavailability prediction models

Pepić, Ivan; Lovrić, Jasmina; Cetina-Čižmek, Biserka; Reichl, Stephan; Filipović-Grčić, Jelena
Toward the practical implementation of eye-related bioavailability prediction models // Drug discovery today, 19 (2014), 1; 31-44 doi:10.1016/j.drudis.2013.08.002 (međunarodna recenzija, pregledni rad, znanstveni)

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Naslov
Toward the practical implementation of eye-related bioavailability prediction models

Autori
Pepić, Ivan ; Lovrić, Jasmina ; Cetina-Čižmek, Biserka ; Reichl, Stephan ; Filipović-Grčić, Jelena

Izvornik
Drug discovery today (1359-6446) 19 (2014), 1; 31-44

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Corneal permeability; cell-based models; tissue-based models; eye-related bioavailability

Sažetak
The development and registration of reformulated ophthalmic products (OPs) requires eye-related bioavailability (BA) assessments. Common BA algorithms associated with other routes of application, such as the oral route, cannot be easily applied to eye-related BA testing. Here, we provide an analysis of the current literature and suggestions for further directions in the development of high-capacity, cost-effective, and highly predictive nonclinical models of eye-related drug BA. One, or a combination of these models, has the potential for routine use in research laboratories and/or the pharmaceutical industry to overcome various obstacles in reformulated OP development and registration.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija



POVEZANOST RADA

Projekti:
006-0061117-1244 - Terapijski nanosustavi (Filipović-Grčić, Jelena, MZOS ) ( CroRIS)

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb

Profili:

Avatar Url Ivan Pepić (autor)

Avatar Url Jelena Filipović-Grčić (autor)

Avatar Url Biserka Cetina-Čižmek (autor)

Avatar Url Jasmina Lovrić (autor)

Poveznice na cjeloviti tekst rada:

doi ac.els-cdn.com www.sciencedirect.com

Citiraj ovu publikaciju:

Pepić, Ivan; Lovrić, Jasmina; Cetina-Čižmek, Biserka; Reichl, Stephan; Filipović-Grčić, Jelena
Toward the practical implementation of eye-related bioavailability prediction models // Drug discovery today, 19 (2014), 1; 31-44 doi:10.1016/j.drudis.2013.08.002 (međunarodna recenzija, pregledni rad, znanstveni)
Pepić, I., Lovrić, J., Cetina-Čižmek, B., Reichl, S. & Filipović-Grčić, J. (2014) Toward the practical implementation of eye-related bioavailability prediction models. Drug discovery today, 19 (1), 31-44 doi:10.1016/j.drudis.2013.08.002.
@article{article, author = {Pepi\'{c}, Ivan and Lovri\'{c}, Jasmina and Cetina-\v{C}i\v{z}mek, Biserka and Reichl, Stephan and Filipovi\'{c}-Gr\v{c}i\'{c}, Jelena}, year = {2014}, pages = {31-44}, DOI = {10.1016/j.drudis.2013.08.002}, keywords = {Corneal permeability, cell-based models, tissue-based models, eye-related bioavailability}, journal = {Drug discovery today}, doi = {10.1016/j.drudis.2013.08.002}, volume = {19}, number = {1}, issn = {1359-6446}, title = {Toward the practical implementation of eye-related bioavailability prediction models}, keyword = {Corneal permeability, cell-based models, tissue-based models, eye-related bioavailability} }
@article{article, author = {Pepi\'{c}, Ivan and Lovri\'{c}, Jasmina and Cetina-\v{C}i\v{z}mek, Biserka and Reichl, Stephan and Filipovi\'{c}-Gr\v{c}i\'{c}, Jelena}, year = {2014}, pages = {31-44}, DOI = {10.1016/j.drudis.2013.08.002}, keywords = {Corneal permeability, cell-based models, tissue-based models, eye-related bioavailability}, journal = {Drug discovery today}, doi = {10.1016/j.drudis.2013.08.002}, volume = {19}, number = {1}, issn = {1359-6446}, title = {Toward the practical implementation of eye-related bioavailability prediction models}, keyword = {Corneal permeability, cell-based models, tissue-based models, eye-related bioavailability} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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