Naslov
Bio-inspired Electrospun Fibre Structures - Numerical Model

Autori
Mijović, Budimir ; Agić, Ante

Izvornik
Journal of fiber bioengineering and informatics (1940-8676) 6 (2013), 1; 23-32

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Electrospun PCL; Multiscale; Numerical Model

Sažetak
A systems approach that integrates processing, structure, property and performance relations has been used in the design of multilevel-structured fibrous materials. For electrospun fibrous structure, numerical implementation of multiscale materials philosophy provides a hierarchy of computational models defining design parameters that are integrated through computational continuum mechanics. Electrospun micro/nano (multiscale) poly("-caprolactone) (PCL) fibrous scaffolds were studied. The fibrous structures were evaluated for their mechanical, morphological and cell attachment properties. The cell attachment studies showed that cell activity on multi-scale scaffolds was higher compared to micro-fibrous scaffolds. These results suggest that the combination of a micro- and nano-fiber hierarchical sca?old could be more beneficial for tissue engineering applications than for individual scaffolds.

Izvorni jezik
Engleski

Znanstvena područja
Strojarstvo, Tekstilna tehnologija

POVEZANOST RADA