Pregled bibliografske jedinice broj: 673470
Expert opinion 2011 on the use of new- antiresorptive agents in the prevention of skeletal-related events in metastatic bone disease
Expert opinion 2011 on the use of new- antiresorptive agents in the prevention of skeletal-related events in metastatic bone disease // Wiener klinische Wochenschrift, 125 (2013), 15/16; 439-447 doi:10.1007/s00508-013-0385-4 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 673470 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Expert opinion 2011 on the use of new- antiresorptive agents in the prevention of skeletal-related events in metastatic bone disease
Autori
Anghel, Rodica ; Bachamann, Alexander ; Beksac, Meral ; Brodowicz, Thomas ; Finek, Jindrich ; Komadina, Radko ; Krzemieniecki, Krzysztof ; Lang, Istvan ; Marencak, Jozef ; Von Moos, Roger ; Pechersttorfer, Martin ; Rordorf, Tamara ; Vrbanec, Damir ; Zielinski, Christoph
Izvornik
Wiener klinische Wochenschrift (0043-5325) 125
(2013), 15/16;
439-447
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
anti-resorptive agents; breast cancer; bone metastases
Sažetak
Bisphosphonates have been a mainstay in the treatment of cancer-related bone disease and have greatly reduced the risk of skeletal complications. More recently, clinical studies suggested additional benefits of denosumab over zoledronic acid in the prevention of skeletal related events. Similar adverse event profiles have been reported for bisphosphonates and denosumab, with infrequent occurrences of osteonecrosis of the jaw with both agents, higher incidence of renal deterioration with zoledronic acid, and higher incidence of hypocalcaemia with denosumab. Based on current evidence, the American Society of Clinical Oncology (ASCO) and National Comprehensive Cancer Network (NCCN) guidelines do not recommend one drug class over the other in patients with metastatic bone disease. Denosumab, however, may present advantages over bisphosphonates in patients suffering from chronic renal insufficiency. Further research and growing clinical experience will refine the evidence based on which decisions in daily clinical practice can be taken.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
108-1080058-0046 - KARCINOM DOJKE-MOLEKULARNE,GENETSKE I KLINIČKE KARAKTERISTIKE (Vrbanec, Damir, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb
Profili:
Damir Vrbanec
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE