Naslov
Current trends in stroke management

Autori
Demarin V., Morović S., Rundek T.

Izvornik
Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti (1330-5301) 517 (2013), 39; 9-33

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
cerebrovascular disease; ischemic stroke; stroke prevention; risk factors; stroke management; thrombolysis; telemedicine; teleneurology

Sažetak
Stroke is a major health problem despite the great efforts made worldwide to fight against it. Despite therapeutic achievements to treat ischemic stroke patients in stroke units with tissue plasminogen activator (tPA), prevention remains the most powerful strategy to cure this complex disease. Stroke is a heterogeneous and multi-factorial disease caused by the combination of vascular risk factors, environment, and genetic factors. These risk factors can be modifiable or non-modifiable. Recently, a great emphasis has been given to the investigations of genetic factors and stroke risk, which may lead to the discovery of new biomarkers for prevention, diagnosis and to the alternative strategies for stroke treatment. Ischemic stroke must be treated as an emergency. Immediate transportation to a nearest hospital, preferably a stroke unit, cautious lowering of excessive blood pressures (>220/120mmHg) and ab stention from heparin and aspirin are the most important measures in the pre- hospital care for a stroke patient. Intravenous thrombolysis in a 3-hour window is the only approved treatment, but it is time-dependent. In severe strokes with occlusion of large intracranial arteries, mechanical recanalization is increasingly used. In order to improve stroke care in rural and urban areas where there is no organized stroke unit, it is useful to establish a stroke network, which functions according to telemedicine and teleneurology rules.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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