Naslov
Impaired learning of motor skills in patients with multiple sclerosis

Autori
Jančuljak, Davor ; Mubrin, Zdenko ; Brzović, Zdravko ; Brinar, Vesna ; Palić, Josip ; Vukašinović, Darko ; Barac, Boško

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 3rd International Congress of Neuropsychiatry / - Kyoto, 2000, 137-137

Skup
International Congress of Neuropsychiatry (3 ; 2000)

Mjesto i datum
Kyoto, Japan, 09.04.2000. - 13.04.2000

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
multiple sclerosis; memory impairment

Sažetak
A group of 55 right-handed inpatients that had met Poser's diagnostic criteria for multiple sclerosis (MS) were matched with a control group of 42 right-handed volunteers in age, sex, and education. The subjects' implicit learning was examined using a computerized test the Motor Skills Task. The task was repeated 10 times for each hand separately. Following variables were analyzed during the trials: total path distances (TD), distance off the target (DOT), time off the target (TOT), and the index DOT/TOT. No difference was found between the subject groups during their TD performance. Patients with MS had in comparison to the controls lower scores on the total DOT performance (p<0.02), longer total TOT (p<0.01), and poorer total index DOT/TOT (p<0.05). During repeated trials the patients had never reached total motor skill performance of the control group. When the performance was analyzed for each hand separately, only the left-hand performances of patients with MS were statistically different from the controls. Lesions of the white matter in a nondominat brain hemisphere had probably caused alteration of the visual-spatial attention that might have contributed to the patients' impairment of motor skill learning.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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