Pregled bibliografske jedinice broj: 668037
Mechanosynthesis of pharmaceutically relevant sulfonyl-(thio)ureas
Mechanosynthesis of pharmaceutically relevant sulfonyl-(thio)ureas // Chemical communications, 50 (2014), 5248-5250 doi:10.1039/C3CC47905F (međunarodna recenzija, članak, znanstveni)
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Naslov
Mechanosynthesis of pharmaceutically relevant sulfonyl-(thio)ureas
Autori
Tan, Davin ; Štrukil, Vjekoslav ; Mottillo, Cristina ; Friščić, Tomislav
Izvornik
Chemical communications (1359-7345) 50
(2014);
5248-5250
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
mechanosynthesis
Sažetak
We demonstrate the first application of mechanochemistry to conduct the synthesis of sulfonyl-(thio)ureas, including known anti-diabetic drugs tolbutamide, chlorpropamide and glibenclamide, in good to excellent isolated yields by either stoichiometric base-assisted or copper-catalysed coupling of sulfonamides and iso(thio)cyanates.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE