Pregled bibliografske jedinice broj: 667213
The Role of APP in Cholesterol Metabolism: A link between Niemann-Pick type C Disease and Alzheimer's Disease
The Role of APP in Cholesterol Metabolism: A link between Niemann-Pick type C Disease and Alzheimer's Disease // Workshop MSLife: High Performance Mass Spectrometry: Integration new tools and methods with Applications in Life Sciences
Konstanz, Njemačka, 2013. (pozvano predavanje, nije recenziran, neobjavljeni rad, znanstveni)
CROSBI ID: 667213 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The Role of APP in Cholesterol Metabolism: A link between Niemann-Pick type C Disease and Alzheimer's Disease
Autori
Katušić Hećimović, Silva
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni
Skup
Workshop MSLife: High Performance Mass Spectrometry: Integration new tools and methods with Applications in Life Sciences
Mjesto i datum
Konstanz, Njemačka, 26.08.2013. - 28.08.2013
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Nije recenziran
Ključne riječi
Alzheimer's disease; APP; amyloid-beta; lysosomal storage diseases; NPC1
Sažetak
We analyzed the processing and trafficking of APP upon cholesterol accumulation in NPC1-null cells. We found enhanced beta-secretase processing of APP and its accumulation within early/recycling endosomes in NPC1-null cells.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
098-0982522-2525 - Mehanizam djelovanja kolesterola u nastanku Alzheimerove bolesti (Katušić Hećimović, Silva, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Profili:
Silva Katušić Hećimović
(autor)
