Naslov
Growth Modulation of Human Osteosarcoma Cells by Mild Oxidative Stress and Novel Synthetic Antioxidants

Autori
Poljak-Blazi, Marija ; Vukovic, Tea ; Hirsl, Nevenka ; Duburs, Gunars ; Cipak, Ana ; Cindric, Marina ; Vigante, Brigita ; Bisenieks, Egils ; Zarkovic, Neven

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
HDIR-1 First Meeting with International Participation 'From Bench to Clinic'

Mjesto i datum
Zagreb, Hrvatska, 11.11.2010

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Synthetic Antioxidants; Mild Oxidative Stress; Growth Modulation

Sažetak
Reactive oxygen species (ROS) and lipid peroxidation products are not only cytotoxic but may also modulate signal transduction in the cells. On the other hand, antioxidants may be considered as modifiers of ROS biological effects. Therefore, the effects of two antioxidants, analogues of 1, 4-dihydropyridine derivatives, cerebrocrast and Z41-74 were investigated for the in vitro growth of human osteosarcoma cells, whose growth was shown to be modulated by oxidative stress and lipid peroxidation.

Izvorni jezik
Engleski

POVEZANOST RADA