Pregled bibliografske jedinice broj: 659159
Skin barrier in atopic dermatitis
Skin barrier in atopic dermatitis // Frontiers in bioscience, 19 (2014), 542-556 doi:10.2741/4225 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 659159 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Skin barrier in atopic dermatitis
Autori
Kezić, Sanja ; Novak, Natalija ; Jakaša, Ivone ; Jungersted, J.M. ; Simon, M. ; Brandner, J.M. ; Middelkamp-Hup, M.A. ; Weidinger, S.
Izvornik
Frontiers in bioscience (1093-9946) 19
(2014);
542-556
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
atopic dermatitis ; skin barrier ; genetics ; immunology
Sažetak
The skin represents the largest organ of the body and provides a vital interface between the body and the environment. Hereditary and acquired alterations of structural proteins and lipids of the stratum corneum and epidermal tight junctions leading to a diminished skin barrier function are major causative factors for a number of skin diseases, in particular atopic dermatitis (AD). This review summarizes current knowledge on the role of the skin barrier in AD with regard to pathogenesis and treatment, on the relationship between skin barrier abnormalities and immune aberrations, and on potential therapies aimed at repair of the skin barrier. Furthermore recent advances in the genetics of AD will be addressed.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
