Naslov
The interplay between sympathetic overactivity, hypertension and heart rate variability

Autori
Drenjančević, Ines ; Grizelj, Ivana ; Haršanji- Drenjančević, Ivana ; Čavka, Ana ; Selthofer- Relatić, Kristina

Izvornik
Acta physiologica Hungarica (0231-424X) 101 (2014); 129-142

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
baroreflex; sympathetic nervous system; blood pressure; hypertension; cardiovascular disease

Sažetak
The control of arterial pressure is a complex interaction of the long- and short-term influences of hormones, local vascular factors, and neural mechanisms. The autonomic nervous system and its sympathetic arm play important roles in the regulation of blood pressure, and over-activity of sympathetic nerves may have an important role in the development of hypertension and related cardiovascular disorders. The baroreceptor system opposes either increases or decreases in arterial pressure, and the primary purpose of the arterial baroreflex is to keep blood pressure close to a particular set point over a relatively short period of time. The ability of the baroreflex to powerfully buffer acute changes in arterial pressure is well established, but the role of the arterial baroreceptor reflex in long-term control of arterial pressure has been a topic of many debate and controversy for decades. The sympathetic nervous system and arterial baroreceptor reflex control of renal sympathetic nerve activity has been proposed to play a role in long-term control of arterial pressure. In this paper, we aim to review the postulated role of sympathetic activation.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA