Pregled bibliografske jedinice broj: 655633
Photoelectron spectroscopy of non-steroidal anti-inflammatory drugs
Photoelectron spectroscopy of non-steroidal anti-inflammatory drugs // Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 112 (2013), 110-115 doi:10.1016/j.saa.2013.04.012 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 655633 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Photoelectron spectroscopy of non-steroidal anti-inflammatory drugs
Autori
Novak, Igor ; Klasinc, Leo ; Chong, Delanopun ; McGlynn, Séan P.
Izvornik
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (1386-1425) 112
(2013);
110-115
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
biological activity ; non-steroidal anti-inflammatory drugs ; photoelectron spectroscopy
Sažetak
The electronic structures of eight non-steroidal anti-inflammatory drugs (NSAIDs) had been studied by UV photoelectron spectroscopy (UPS) and high-level Green's function (GF) calculations. Our UPS data show that the electronic structure influences the measured biological activity of NSAID, but that it is not the dominating factor. The role of electronic structure needs to be considered in conjunction with other factors like steric properties of the COX active site and orientation of relevant residues in the same site
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
098-0982915-2945 - Spektroskopija, kemijska svojstva i reakcije biološki aktivnih molekula (Kovač, Branka, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
