Naslov
Accidental plant poisoning with Colchicum autumnale: report of two cases

Autori
Brnčić, Nada ; Višković, Ivica ; Perić, Relja ; Đirlić, Anđelko ; Vitezić, Dinko ; Cuculić, Dražen

Izvornik
Croatian medical journal (0353-9504) 42 (2001), 6; 673-675

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
alkaloids ; colchicine ; diarrhea ; multiple organ failure ; plant poisoning ; plants medicinal ; toxicology

Sažetak
Colchicine poisoning is a rare but serious and potentially fatal event, which results from food poisoning or overdose with drugs containing colchicine, with no currently available antidote. We report two cases of plant poisoning with Colchicum autumnale, in which the patients had identical initial symptoms but developed extremely different clinical courses. One patient recovered after only moderate gastroenteritis and liver injury, whereas the other died of rapid progressive multiple organ failure 52 h after the plant ingestion. We recommend that all patients suspected of colchicine intoxication due to its unpredictable outcome should be managed according to the principles of intensive care, irrespective of the actual degree of poisoning.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA