Naslov
Transfusion reactions in Croatia 2010

Autori
Šarlija, Dorotea ; Štimac, Ružica ; Vuk, Tomislav ; Jukić, Irena

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Programme and Abstracts of XIV International Haemovigilance Seminar / - Montréal : Public Health Agency of Canada, 2012

Skup
XIV International Haemovigilance Seminar

Mjesto i datum
Montréal, Kanada, 25.04.2012. - 27.04.2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
transfusion reactions

Sažetak
Background According to the By-Law on the System of Traceability of Blood Components and Monitoring of Serious Adverse Reactions (SAR) and Serious Adverse Events (SAE) from 2007, institutions providing transfusion treatment have been included in systematic surveillance of transfusion treatment in Croatia. Materials and Methods Reactions associated with transfusion treatment were reported on the uniform form through hospital transfusion departments to the Croatian Institute of Transfusion Medicine (CITM). Annual reports on transfusion reactions recorded in 2010 were submitted by 34 institutions out of 36. Out of the 34 institutions having submitted reaction reports, 15 institutions prepare and use blood components (hospital blood establishment), whereas 19 institutions are only engaged in blood product utilization (hospital blood bank). Results In 2010, blood was collected from 177 355 blood donors. According to data available, 286 061 blood components were issued for transfusion therapy, including 159 238 red blood cells (RBC), 76 833 platelets and 49 990 fresh frozen plasma. A total of 375 transfusion reactions or 1.3/1000 blood components issued for transfusion therapy were reported, predominated by febrile nonhemolytic transfusion reactions (46.13%) and allergic reactions (38.93%), followed by reactions classified as 'Other' (5.87%) and delayed hemolytic transfusion reactions (4.00%). Out of 375 transfusion reactions reported, 75% referred to RBC, 14% to plasma, and 11% to platelet blood components. On report reassessment, 32 transfusion reactions or 0.1/1000 blood components issued for transfusion therapy were characterized as serious adverse reactions: acute hemolytic transfusion reaction (AHTR) 1 with lethal outcome, 15 delayed hemolytic transfusion reactions (DHTR), 6 anaphylactic reactions, 1 anaphylactic shock, 1 transfusion-related acute lung injury (TRALI), 2 transfusion associated dyspnea (TAD), 1 post- transfusion purpura (PTP), 3 transfusion associated circulatory overload (TACO) and 2 transfusion transmitted viral infections (TTVI). Conclusion In order to make it available to the public, 2010 National Report has been published in the Croatian Transfusion Gazette.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA