Naslov
Accumulated metals and metallothionein expression in organs of hares (Lepus europaeus Pallas) within natural gas fields of Podravina, Croatia

Autori
Tota, Marin ; Jakovac, Hrvoje ; Špirić, Zdravko ; Srebočan, Emil ; Milin, Čedomila

Izvornik
Archives of environmental & occupational health (1933-8244) 70 (2015), 3; 126-132

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
hares; zinc; copper; metallothionein; environment

Sažetak
Environmental impact of natural gas facility near Molve (Podravina, Croatia) was assessed using hares (Lepus europaeus Pallas) as biomonitors. Elevated levels of heavy metals in the environment lead to their accumulation in different tissues of hares. We have tested accumulation and distribution of several metals in hares liver, kidney and muscle tissue. The accumulation of copper in hares liver and kidneys with concomitant decrease of zinc was observed in animals from Podravina region as opposed to control group of animals (Island Krk, Croatia). Secondly, the expression of metallothioneins was assessed because of their crucial role in metal homeostasis. Observed elevation of metallothionein expression in tested organs emphasizes the possible prolonged negative effects of heavy metals in the surroundings as well as a state of oxidative stress in animals. Further monitoring of the area is necessary for better control of hydrocarbon processing to diminish the possible negative environmental effects.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti

POVEZANOST RADA